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A Level Biology

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Course Content

chapter1: The Variety of Living Organisms
1.1 Introduction to Biology The study of living organisms and their interactions with the environment. Importance of understanding biological principles for health, conservation, and technology. 1.2 Characteristics of Living Organisms MRS GREN: Movement: Changes in position or movement of substances. Respiration: Release of energy from food. Sensitivity: Responding to changes in the environment. Growth: Increase in size and mass. Reproduction: Producing new organisms. Excretion: Removal of waste substances. Nutrition: Taking in and using food. 1.3 Cell Theory and Cell Structure All living organisms are made of cells. Basic unit of life. Cell types: Prokaryotic (e.g., bacteria): No nucleus. Eukaryotic (e.g., plant and animal cells): Has a nucleus. 1.4 The Diversity of Living Organisms Bacteria, fungi, plants, animals, and protists. Differences and similarities between these groups. 1.5 Classification of Living Organisms Hierarchical system: kingdom, phylum, class, order, family, genus, species. Binomial classification: Genus + species name (e.g., Homo sapiens). 1.6 The Importance of Classification Helps scientists organize living organisms. Assists in identification and study of species. 1.7 Microscopes Magnification and resolution. Types: Light microscopes, electron microscopes. Use in observing cells and microorganisms. 1.8 Practical Skills Handling microscopes. Preparing slides. Calculating magnification and size of objects

Chapter 2: Cells and Cell Organisation
2.1 The Cell Cycle and Cell Division Importance of cell division for growth and repair. The stages of mitosis: prophase, metaphase, anaphase, telophase. Differences between mitosis and meiosis. The cell cycle: growth (interphase), mitosis, cytokinesis. 2.2 Differentiation and Specialised Cells How cells change to perform specific functions. Example: nerve cells, muscle cells, xylem and phloem in plants. The importance of differentiation in multicellular organisms. 2.3 Cell Organisation in Plants and Animals Tissues, organs, and systems. Plant tissues: meristematic, xylem, phloem, epidermis. Animal tissues: epithelial, muscle, nerve tissues. 2.4 Microscopy and Cell Structure Use of microscopes to observe cells. Differences between light microscopy and electron microscopy. Cell structure details: nucleus, cytoplasm, cell membrane, cell wall, vacuole, chloroplasts. 2.5 Culturing Microorganisms Growing bacteria and fungi in the lab. Conditions needed for cultures to grow. Safety precautions. 2.6 Practical Skills Preparing slides. Using microscopes. Calculating magnification and size of cell structures.

Chapter 3: Transport in Plants
3.1 The Need for Transport Systems Why plants need transport systems to move water, minerals, and food. Differences between simple diffusion and active transport. 3.2 The Structure of the Xylem and Phloem Xylem transports water and minerals from roots to leaves. Phloem transports food (sugar) from leaves to other parts. Structure of xylem: thick walls, dead cells. Structure of phloem: living cells, sieve tubes, companion cells. 3.3 How Water Is Absorbed and Transported The process of osmosis in root hair cells. Root pressure. Capillary action. Transpiration: the evaporation of water from leaves. 3.4 The Transpiration Stream The pathway of water movement through the plant. Factors affecting transpiration: light, humidity, temperature, wind. 3.5 The Role of Transpiration Cooling the plant. Supply of minerals. Maintaining the flow of water and nutrients. 3.6 Factors Affecting Transpiration How environmental conditions influence water loss. Adaptations to reduce water loss (e.g., waxy cuticle, stomatal closure). 3.7 Controlling Water Loss Stomatal regulation. Methods to measure transpiration (e.g., potometer).

Chapter 4: Nutrition in Animals
4.1 The Need for Food To provide energy for respiration. For growth and repair. To maintain body temperature. To keep the organism healthy. 4.2 Balanced Diet Contains the right proportions of carbohydrates, proteins, fats, vitamins, minerals, and water. The importance of each component: Carbohydrates: main energy source. Proteins: growth and repair. Fats: concentrated energy store. Vitamins and minerals: metabolic processes and health. Water: vital for life processes. 4.3 Modes of Nutrition Autotrophic (plants make their own food via photosynthesis). Heterotrophic (animals consume other organisms). 4.4 The Human Digestive System Structure and function: Mouth, oesophagus, stomach, small intestine, large intestine, rectum, anus. Accessory organs: liver, gall bladder, pancreas. Process of digestion: Mechanical digestion (chewing, churning). Chemical digestion (enzymes breaking down food). 4.5 Enzymes in Digestion Types of enzymes: Amylase (starch to sugar). Proteases (proteins to amino acids). Lipases (fats to fatty acids and glycerol). Suitable pH and conditions for each enzyme. 4.6 Absorption of Nutrients Villis in the small intestine for absorption. Transport of nutrients to the bloodstream. 4.7 The Role of the Liver Produces bile to emulsify fats. Detoxifies harmful substances. Regulates blood sugar levels. 4.8 The Human Digestive System Disorders (optional) Common disorders like tooth decay, indigestion, diarrhea, constipation.

Chapter 5: The Circulatory System
5.1 The Need for a Circulatory System To transport oxygen, nutrients, hormones, and waste products. To connect different parts of the body. 5.2 Structure of the Heart Location and size. Four chambers: right atrium, right ventricle, left atrium, left ventricle. Valves to prevent backflow. 5.3 The Blood Vessels Arteries: carry blood away from the heart, thick muscular walls. Veins: carry blood to the heart, thinner walls. Capillaries: tiny vessels for exchange of materials. 5.4 The Blood Components: Red blood cells: carry oxygen (contain hemoglobin). White blood cells: defend against infection. Plasma: transport nutrients, hormones, waste. Platelets: involved in clotting. 5.5 Cardiac Cycle The process of heart contraction and relaxation. How the heart pumps blood. 5.6 Blood Pressure Measurement and significance. Factors affecting blood pressure. 5.7 The Lymphatic System (optional) Role in immune response and fluid balance. 5.8 Health and Circulatory Disorders Coronary heart disease. Atherosclerosis. Hypertension. Effects of smoking, diet, and exercise.

Chapter 6: Response to Exercise and the Nervous System
6.1 The Need for Response Systems To maintain a steady internal environment (homeostasis). To respond to changes in the environment or activity level. 6.2 The Nervous System Main parts: Central nervous system (CNS): brain and spinal cord. Peripheral nervous system (PNS): nerves extending from CNS. Types of nerves: Sensory nerves: carry impulses to CNS. Motor nerves: carry impulses from CNS to effectors. Relay nerves: connect sensory and motor nerves. 6.3 The Structure of a Neuron Dendrites, cell body, axon, myelin sheath, nerve ending. How impulses travel along neurons. 6.4 The Nervous Pathway Reflex actions: Stimulus, receptor, sensory neuron, relay neuron, motor neuron, effector, response. Examples of reflexes (e.g., knee jerk, blinking). 6.5 The Brain and Spinal Cord Structure and functions. The cerebrum, cerebellum, medulla. The spinal cord and reflex arcs. 6.6 Sensory and Motor Receptors Detect stimuli like light, sound, pressure, chemicals. Responsive effectors: muscles and glands. 6.7 The Effect of Exercise on the Body Increased heart rate and breathing rate. Role of adrenaline. Muscle fatigue and recovery. 6.8 The Role of Hormones How hormones like adrenaline prepare the body for exercise (fight or flight response).

Chapter 7: Energy and Respiration
7.1 The Importance of Energy To power metabolic processes. For growth, movement, and maintaining body temperature. 7.2 Photosynthesis (brief overview if covered) Process by which plants convert light energy into chemical energy. ​ The role of chlorophyll in chloroplasts. 7.3 Respiration – The Energy Release The process of releasing energy from glucose. Types: Aerobic respiration (with oxygen). Anaerobic respiration (without oxygen). 7.4 Aerobic Respiration Occurs in the mitochondria. Produces a large amount of ATP (energy). 7.5 Anaerobic Respiration Occurs in oxygen-deficient conditions. In animals: produces lactic acid. In yeast and bacteria: produces ethanol and carbon dioxide. 7.6 The Use of Energy in Living Organisms Active transport. Muscle contraction. Reproduction and growth. Maintaining body temperature. 7.7 Effect of Exercise on Respiration Increased demand for oxygen. Oxygen debt and recovery. 7.8 Measuring Respiration Practical methods: respirometers. Indicators of respiration activity.

Chapter 8: Homeostasis and the Kidney
8.1 The Importance of Homeostasis Maintaining a stable internal environment. Examples include regulation of temperature, water, and ions. 8.2 The Role of the Kidneys in Homeostasis Filtering blood to remove waste products. Regulating water and mineral ion levels. Producing urine. 8.3 Structure of the Kidney Cortex, medulla, pelvis. Nephrons as the functional units. 8.4 The Nephron and Its Functions Structures: Bowman's capsule, renal tubule, Loop of Henle, collecting duct. Processes: Filtration at Bowman's capsule. Reabsorption of glucose, ions, and water. Secretion of waste products. 8.5 The Composition of Urine Water, urea, salts. The concentration of urine depends on the body's hydration level. 8.6 The Control of Water Content The role of the hormone ADH (antidiuretic hormone). How ADH influences the permeability of the collecting duct. Effect of alcohol and other substances on ADH. 8.7 Effects of Imbalances Dehydration (high urine concentration). Overhydration (dilute urine). Kidney failure and dialysis. 8.8 Practical Skills Testing urine for sugar and protein. Investigating water balance in the body.

Chapter 9: Reproduction in Humans
9.1 The Purpose of Reproduction Producing offspring to continue the species. Ensuring survival and adaptation. 9.2 Types of Reproduction Sexual reproduction: involves male and female gametes. Asexual reproduction: involves only one parent (not common in humans). 9.3 The Male Reproductive System Main organs: testes, sperm ducts, prostate gland, penis. Structure and function of testes. Production of sperm in seminiferous tubules. The role of testosterone. 9.4 The Female Reproductive System Main organs: ovaries, oviducts (fallopian tubes), uterus, vagina. Oogenesis: formation of ova (egg cells). Function of the ovaries and the menstrual cycle. 9.5 Fertilization and Pregnancy Fusion of sperm and egg to form zygote. The role of the fallopian tube. Embryonic development. Implantation in the uterus. 9.6 The Menstrual Cycle Phases: menstruation, follicular phase, ovulation, luteal phase. Hormones involved: FSH, LH, estrogen, progesterone. Regulation by hormones. 9.7 Pregnancy and Childbirth Development of an embryo and fetus. Nutritional needs during pregnancy. Baby delivery process. 9.8 Reproductive Technologies (optional) Contraception methods. In-vitro fertilization (IVF). Ethical considerations.

Chapter 10: Inheritance, Variation, and Evolution
10.1 Types of Reproduction and Genetic Variation Sexual reproduction leads to genetic variation. Asexual reproduction produces clones with little variation. 10.2 Genes and Chromosomes Genes are units of inheritance. Located on chromosomes within the nucleus. Human chromosome number: 46 (23 pairs). 10.3 DNA Structure and Gene Function Double helix structure. Genes contain instructions for making proteins. 10.4 Alleles and Genotypes Different forms of a gene: alleles. Genotype: genetic makeup. Phenotype: observable characteristics. 10.5 Dominant and Recessive Alleles Dominant alleles mask the effect of recessive alleles. Representation (e.g., T for tall, t for short). 10.6 Inheritance and Punnett Squares Predict possible offspring genotypes. Examples with monohybrid crosses. 10.7 Human Blood Groups The ABO blood group system. Blood group inheritance (genotypes and phenotypes). 10.8 Evolution and Natural Selection Organisms change over time. The role of mutations. Survival of the fittest and adaptation. 10.9 Speciation Formation of new species. Isolating mechanisms. 10.10 Evidence for Evolution Fossil record. Comparative anatomy and embryology. Genetic evidence.

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